THE IMPACT OF POLYMICROBIAL INFECTIONS ON URINARY TRACT INFECTIONS & ANTIBIOTIC RESISTANCE

Traditional culture misses a significant percentage of organisms in urine which is no longeconsidered a ‘sterile’ environment. New information suggests that many infections are polymicrobial in nature and these mutualistic interactions can potentially enhance infection as well as resistance to antibiotics. GUIDANCE combines the latest technology in microbial DNA detection with a phenotypic, functional assay […]

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Guidance Specimen Collection Guide

Specimen Collection Quick Reference Guide. Molecular Testing for: Interstitial Cystitis; Recurrent, Persistant, or Complicated UTI; Prostatitis; Simple Cystitis.

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A LONG-TERM UTI SOLUTION FOR HEALTHIER PATIENTS IN YOUR LONG-TERM CARE

In long-term care, UTIs are a major cause of unnecessary spending and declining patient health. But a solution is easier than you might expect…

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The Clinical Urine Culture

Enhanced quantitative urine culture (EQUC) detects live microorganisms in the vast majority of urine specimens reported as “no growth” by the standard urine culture protocol. Here, we evaluated an expanded set of EQUC conditions (expanded-spectrum EQUC) to identify an optimal version that provides a more complete description of uropathogens …

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Urine Is Not Sterile

Our previous study showed that bacterial genomes can be identified using 16S rRNA sequencing in urine specimens of both symptomatic and asymptomatic patients who are culture negative according to standard urine culture protocols. In the present study, we used a modified culture protocol that included plating larger volumes of urine …

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Increased human pathogenic potential

The current diagnostic standard procedure outlined by the Health Protection Agency for urinary tract infections (UTIs) in clinical laboratories does not report bacteria isolated from samples containing three or more different bacterial species. As a result many UTIs go unreported and untreated, particularly in elderly patients…

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THE HIDDEN WORLD OF THE BLADDER MICROBIOME

Within mouse models, bladders first infected with Group B Streptococcus (GBS) down regulates the host immune response through the release of capsule sialic acids allowing co-infected UPEC to survive within the lumen of the bladder as such alter the long-term outcomes of the infection as there is an increased risk of ascending kidney infections …

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SWIFT DIAGNOSIS AND THERAPY OPTIONS THAT WORK THE FIRST TIME TAKE GUIDANCE

Today’s standard of care simply isn’t good enough. Typical urine culture misses up to 2/3 of all UTI-positive patients and it detects organisms in only 4% of the cases to diagnose prostatitis…

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Microorganism List for Guidance

Guidance accurately identifies pathogenic strains of microbes associated with urinary tract infections (UTIs). Below you will find explanations of each type of bacterial agentidentified in our Guidance test…

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