Guidance Hematuria is a unique rapid molecular test that identifies pathogens that may be causing asymptomatic hematuria. Malignancy is diagnosed in less than 10% of cases with microscopic hematuria, yet the most common presenting symptom of viral UTI is hemorrhagic cystitis. If the cause for hematuria is infectious, the detected pathogen will require a distinct treatment plan. You’ll need to identify the pathogen to create the right treatment plan.


Asymptomatic microscopic or gross hematuria.

Sample Requirements
2 gray top tubes of 4 mL midstream or catheterized urine.

Note: 8 mL midstream urine in yellow top tube required for urinary analysis.

Clinical Utility
AUA guidelines suggest upon the discovery of hematuria, an assessment of the asymptomatic microhematuria patient should include:

  • A careful history, physical examination, and laboratory examination to rule out causes of asymptomatic microhematuria such as infection
  • Once the benign causes have been ruled out, the presence of asymptomatic microhematuria should prompt a urologic evaluation1

Guidance Hematuria is designed to assist in ruling out or ruling in an infectious cause for hematuria.

The test detects:

AdenovirusBK VirusJC Virus
HHV-1,-2 (HSV 1 & 2)HHV-3 (VZV)HHV-4 (EBV)
Mycobacterium aviumMycobacterium tuberculosisStreptococcus pyogenes