GUIDANCE® UTI

GUIDANCE® UTI

THE RIGHT UTI THERAPY
RIGHT FROM THE START.

Guidance UTI is the only diagnostic test for both pathogen identification and antibiotic sensitivity that’s backed by patented technology. It’s time to provide your patients with personalized therapy options that work the first time.

BYPASS CHALLENGES AND ARRIVE AT SOLUTIONS—IN 48 HOURS.

Traditional urine culture misses up to 22% of all UTI-positive patients.1

Guidance UTI detects 33% more organisms than culture. We cover the most relevant causes of UTIs with a high degree of sensitivity, for a more accurate diagnosis.
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Genotype testing alone only provides information about the genetic potential to develop resistance to antibiotics.

Guidance UTI is the only test that also includes Pooled Antibiotic Susceptibility Testing (P-AST™) to determine treatments that will be effective against the pool of organisms as they grow and interact in the presence of antibiotics.

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Delayed personalized treatment happens consistently with traditional culture methods taking up to three days or more to return results.

Guidance UTI delivers results within 48 hours of a sample reaching the lab, for fast, personalized treatment that advances patient outcomes and antibiotic stewardship.

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WE’RE HERE TO HELP YOU OVERCOME UNRESOLVED UTIs QUICKLY.

My Patient’s UTI story

A video series dedicated to Urologists and the topic of urinary tract infections

START WITH THE RIGHT TEST, RIGHT AWAY.

Who needs Guidance UTI?

Patients with symptoms consistent with:
  • Recurrent UTI
  • Interstitial cystitis
  • Pyelonephritis
  • Prostatitis
At-risk groups:
  • Pregnant
  • Elderly
  • Diabetic 
  • On chronic pain care regimens
  • Immunosuppressed
  • Men with UTIs
  • Past urinary culture results were “contaminated” 
    or negative 

What does Guidance UTI test for?

In addition to the often-tested organisms Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, and Staphylococcus aureus, we also test for an extremely comprehensive list of pathogens.

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BACTERIAL/YEAST ORGANISMS:
  • Acinetobacter baumannii
  • Actinotignum schaalii
  • Aerococcus urinae
  • Alloscardovia omnicolens
  • Candida albicans
  • Candida glabrata
  • Candida parapsilosis
  • Citrobacter freundii
  • Citrobacter koseri
  • Corynebacterium riegelii
  • Klebsiella aerogenes
  • Enterococcus faecalis
  • Escherichia coli
  • Klebsiella oxytoca
  • Acinetobacter baumannii
  • Actinobaculum schaalii
  • Aerococcus urinae
  • Alloscardovia omnicolens
  • Candida albicans
  • Candida glabrata
  • Candida parapsilosis
  • Citrobacter freundii
  • Citrobacter koseri
  • Corynebacterium riegelii
  • Enterobacter aerogenes
  • Enterococcus faecalis
  • Escherichia coli
  • Klebsiella oxytoca
  • Klebsiella pneumoniae
  • Morganella morganii
  • Mycobacterium tuberculosis
  • Mycoplasma genitalium
  • Mycoplasma hominis
  • Pantoea agglomerans
  • Proteus mirabilis
  • Providencia stuartii
  • Pseudomonas aeruginosa
  • Serratia marcescens
  • Staphylococcus aureus
  • Streptococcus agalactiae
  • Streptococcus pyogenes
  • Ureaplasma urealyticum
BACTERIAL GROUPS:
  • Coagulase-neg. staphylococci*
  • Viridans group streptococci†
VIRAL PARTICLES:
  • BK virus
  • Adenovirus
  • CMV
  • HHV-6
  • HHV-7
  • HSV-1&2
  • JC virus
  • Klebsiella pneumoniae
  • Morganella morganii
  • Mycobacterium tuberculosis
  • Mycoplasma genitalium
  • Mycoplasma hominis
  • Pantoea agglomerans
  • Proteus mirabilis
  • Providencia stuartii
  • Pseudomonas aeruginosa
  • Serratia marcescens
  • Staphylococcus aureus
  • Streptococcus agalactiae
  • Streptococcus pyogenes
  • Ureaplasma urealyticum
SEXUALLY TRANSMITTED ORGANISMS:
  • Chlamydia trachomatis
  • Neisseria gonorrhoeae
  • Trichomonas vaginalis
KEY
  • Guidance Basic | Guidance Comprehensive
  • Guidance Comprehensive only
  • Add-on tests

*Coagulase-neg. staphylococci: Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus lugdunensis, Staphylococcus saprophyticus

†Viridans group streptococci: Streptococcus anginosus,
Streptococcus oralis, Streptococcus pasteuranus

How does Guidance UTI recommend treatment?

We leverage a dual assessment—genotype resistance and Pooled Antibiotic Susceptibility Testing (P-AST)—to uncover more effective, personalized therapy options.

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Pooled Antibiotic Susceptibility Testing (P-AST) includes:
  • Ampicillin (PO/IV)
  • Ampicillin/Sulbactam (IV)
  • Amoxicillin/Clavulanate (PO)
  • Cefaclor (PO)
  • Cefazolin (IV)
  • Cefepime (IV)
  • Cefoxitin (IV)
  • Ceftazidime (IV)
  • Ceftriaxone (IM/IV)
  • Ciprofloxacin (PO/IV)
  • Ampicillin (PO/IV)
  • Ampicillin/Sulbactam (IV)
  • Amoxicillin/Clavulanate (PO)
  • Cefaclor (PO)
  • Cefazolin (IV)
  • Cefepime (IV)
  • Cefoxitin (IV)
  • Ceftazidime (IV)
  • Ceftriaxone (IM/IV)
  • Ciprofloxacin (PO/IV)
  • Fosfomycin (PO/IV)
  • Gentamicin (IM/IV)
  • Levofloxacin (PO)
  • Meropenem (IV)
  • Nitrofurantoin (PO)
  • Piperacillin/Tazobactam (IV)
  • Sulfamethoxazole/Trimethoprim (PO/IV)
  • Tetracycline (PO)
  • Vancomycin (IV)
Genotype antibiotic resistance testing includes:
  • Ampicillin
  • Beta-Lactamase
  • Carbapenem
  • Extended Spectrum Beta-Lactamase
  • Macrolide
  • Methicillin
  • Quinolinone/Fluoroquinolone
  • Vancomycin
  • Fosfomycin (PO/IV)
  • Gentamicin (IM/IV)
  • Levofloxacin (PO)
  • Meropenem (IV)
  • Nitrofurantoin (PO)
  • Piperacillin/Tazobactam (IV)
  • Sulfamethoxazole/Trimethoprim (PO/IV)
  • Tetracycline (PO)
  • Vancomycin (IV)
KEY
  • Guidance Basic | Guidance Comprehensive

WHAT IS THE TESTING METHODOLOGY FOR GUIDANCE UTI? 

Pathnostics’ GUIDANCE UTI Test utilizes PCR amplification for the targeted detection of agents. Pathogens are reported in ranges of organism(s) per milliliter of urine.

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DIAGNOSE THE PROBLEM AT THE SOURCE.

Guidance UTI leverages molecular technology to detect more pathogens than traditional culture methods with a high degree of sensitivity, resulting in a more accurate diagnosis.

View Chart

UNDERSTAND HOW TO ACCURATELY TREAT UTIs.

In populations 65 and older, the rate of polymicrobial infections could be as high as 39%.2 In these infections, bacterial species interact to either increase or decrease resistance against antibiotics. 3–7

To determine if pathogens have antibiotic resistance, some clinicians rely on the presence or absence of resistance genes (i.e., genotype testing). However, genotyping only reveals the genetic potential to develop resistance and does not determine what treatment will be effective against the pool of organisms.

Only Guidance UTI goes beyond genotype resistance testing by also including Pooled Antibiotic Susceptibility Testing (P-AST) to determine which treatment will be most effective against the pool of organisms as they grow and interact in the presence of antibiotics.

TAKE THE FAST TRACK TO EFFECTIVE THERAPY.

Traditional culture methods take up to three days or more to return results, requiring physicians to treat UTIs empirically while they wait. This can lead to overprescribing and antibiotic resistance. Guidance UTI delivers results in as quickly as 48 hours, enabling physicians to dispense precise, personalized treatment the first time, which ultimately advances patient care and antibiotic stewardship initiatives.

WORKFLOW TURNAROUND TIME

THE COMPLETE PATIENT PICTURE AT A GLANCE.

The Guidance UTI report displays personalized therapy options to help speed the road to recovery.

DOWNLOAD REPORT

GET GUIDANCE UTI NOW

Ready to provide your patients with personalized therapy options that work the first time?

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